If you had a tape-secured PIV, then you would have to remove the tape to change the tubing.
StatLock™ IV Ultra Stabilisation Device
With the StatLock™ IV Ultra Stabilisation Device you can keep the stabilisation device in place while you change tubing. Simply steady the retainer with the thumb and index finger of one hand while unscrewing the extension set. Remove the set. Then, while continuing to brace the retainer, press-fit and screw in your replacement extension set.
StatLock™ IV Select Stabilisation Device
For StatLock™ IV Select Stabilisation Device, you will need to replace the StatLock™ Stabilisation Devices when you remove and replace the tubing – just as you would with tape securement; but this is a rare event offset by StatLock™ Stabilisation Device advantages.