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BD Phoenix™ M50 Instrument

Delivering performance, connectivity and functionality required by clinical microbiology laboratories

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Overview

The BD Phoenix™ M50 instrument provides clinicians with accurate and timely identification and susceptibility results that might guide choice of therapy and patient management.

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Features and Benefits
Trusted performance

The BD Phoenix™ system provides on-panel doubling dilutions of antimicrobials and built-in detection resistance, including CPO, MRSA, mecA, VRSA, VRE, ESBL, HLAR, and iMLSb*.

Scalability
The instrument is compact and stackable, allowing for increased testing volumes by doubling capacity within the same footprint.
Advanced data management

The BD EpiCenter™ data management system interfaces with the BD Phoenix™ M50 and provides intuitive, on-demand antibiogram generation and flexible reporting options.

Dual growth detection technology

The BD Phoenix™ M50 instrument determines growth using both an oxidation-reduction indicator and turbidity growth detection to help provide both rapid and accurate susceptibility results.

True doubling dilutions

The BD Phoenix™ system utilises on-panel doubling dilutions of antimicrobial concentrations for determination of MIC results.

Delayed growth algorithm

The BD Phoenix™ M50 instrument employs a delayed growth algorithm that may defer reporting for slow-growing organisms until additional instrument readings are collected. This feature enables an accurate determination of growth or no-growth, providing additional assurance that results are accurate.

Resistance detection

The BD Phoenix™ system provides on-panel doubling dilutions of antimicrobials and built-in detection of resistance, including CPO, MRSA, mecA, VRSA, VRE, ESBL, HLAR, and iMLSb*.

Robust, customisable data management

The BD EpiCenter™ data management system offers the BDXpert system, which implements CLSI/EUCAST breakpoints and SIR interpretations. BD EpiCARE™ is an optional extension of the BD EpiCenter™ system that gives users the ability to define customised rules and actions to ensure compliance for the reporting of microbiology data that may be specific to their organisation.

Modular and scalable

The BD Phoenix™ M50 instrument offers a compact and stackable design (up to two instruments) that allows for increased testing volumes by doubling capacity within the same footprint.

Ease of use

The system requires minimal maintenance, no reagent additions post inoculation and few supplemental tests for final result determination, and utilises leak-resistant, room-temperature panel storage.

Automated inoculation preparation

The BD Phoenix™ AP automated inoculation preparation instrument may help to reduce sample preparation workflow burdens, reducing total hands-on time per sample by 50% compared to manual BD Phoenix™. 1

Microorganism identification

  • The BD Phoenix M50 system instrument offers identification-only panels and combination ID/AST panels, using 51 wells for identification substrates.
  • The system can provide rapid identification of most clinically significant Gram-negative and Gram-positive bacteria, as well as yeast.

Antimicrobial Susceptibility testing

  • The BD Phoenix M50 system offers 85 wells for antimicrobial dilutions on standard AST-only panels and combination ID/AST panels, and 136 wells on the BD Phoenix Emerge panel.
  • The instrument can provide susceptibility results for most clinically significant Gram-negative and Gram-positive bacteria.
  • The BD Phoenix M50 system panels test for several resistance markers* such as** :
    • Gram-positive bacteria
      • HLAR—High Level Aminoglycoside Resistant Enterococcus
      • iMLSb—Inducible Clindamycin Resistance
      • MRSA—based on Oxacillin Interpretation with Staphylococcus species
      • mecA – detection of mecA-mediated resistance in Staphylococcus aureus
      • BL- Staphylococcus ß-Lactamase (Nitrocefin based test)
      • VRSA—Vancomycin-Resistant Staphylococcus aureus
      • VRE—based on Vancomycin interpretation
    • Gram-negative bacteria
      • CPO—Carbapenemase Producing Organism
      • ESBL—offered on Gram-negative panels and requires no additional disc diffusion or E-Test confirmation.

Detecting CPOs

  • The BD Phoenix CPO detect test, available on certain BD Phoenix Gram-negative panels, provides information, including Ambler classification, to help guide clinicians in their treatment decisions.
  • This test is available in two-panel configurations that allow microbiology labs to test for CPOs as part of routine susceptibility testing on BD Phoenix panels:
    • 2-well configuration—provides detection of Carbapenemase-producing organisms in Enterobacterales, Pseudomonas aeruginosa and Acinetobacter baumannii
    • 9-well configuration—provides detection of carbapenemase-producing organisms and Ambler classification (A, B or D) in Enterobacterales, Pseudomonas aeruginosa and Acinetobacter baumannii
  • The BD Phoenix CPO detect test is currently the only phenotypic test on an automated AST system that provides CPO detection and Ambler classification.
  • On average, the BD Phoenix CPO detect test detects and classifies CPOs from isolated colonies within 6 to 11 hours.**
EIFUs
Resources
References

Please note, not all products, services or features of products and services may be available in your local area. Please check with your local BD representative.

*Depending on BD Phoenix panel type and organism identification.
**BD internal studies—data on file

Reference
  1. Junkins A, et al. Comparison of BD Phoenix AP Workflow with Vitek 2. J. Clin. Microbiol. 2010. 48 (5): 1929-1931. Study was supported by grants from BD Diagnostic Systems.

BD-38368

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